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Pneumonia is an inflammatory condition of the lung―affecting primarily the microscopic air sacs known as alveoli. Typical symptoms include a cough, chest pain, fever, and difficulty breathing.

Hospital-acquired pneumonia (HAP) or nosocomial pneumonia refers to any pneumonia contracted by a patient in a hospital at least 48–72 hours after being admitted. It is usually caused by a bacterial infection
Ventilator-associated pneumonia (VAP) is a sub-type of hospital-acquired pneumonia (HAP) which occurs in people who are receiving mechanical ventilation.

Causative organisms:-
Lower respiratory tract infections (LRTI)

Nosocomial and community acquired pneumonia caused by:

Pseudomonas aeruginosa Staphylococcus aureus (methicillin-susceptible strains) Streptococcus pneumoniae Escherichia coli Haemophilus influenzae
S. Pneumoniae H. influenzae

Gastroenteritis : A syndrome characterized by gastrointestinal symptoms including nausea, vomiting, diarrhea and abdominal discomfort

Diarrhea :  Abnormal fecal discharge characterized by frequent and/or fluid stool; usually resulting from disease of the small intestine and involving increased fluid and electrolyte loss.

Dysentery:-  An inflammatory disorder of the gastrointestinal tract often associated with blood and pus in the feces and accompanied by symptoms of pain, fever, abdominal cramps; usually resulting fromdisease of the large intestine

Enterocolitis : Inflammation involving the mucosa of both the small and large intestine . Important Pathogens responsible for GI infections

Caustive organisms:-

Cіtrobacter spp., Campylobacter jejunі, Cardnerella vagіnalіs, Enterobacter spp., Escherіchіa colі,Proteus spp.,  Salmonella spp., Serratia spp., Shіgella spp., Yersinia enterocolіtіca, Bacteroides spp. except Bacteroides fragilis , including B. melanіnogenіcus and other oral cavity microorganisms referred to bacteroides; Clostridium perfrіngens; Fusobacterіum spp.;

Gram-negative aerobes: Acіnetobacter spp., Aeromonas hydrophіla, Capnocytophaga spp., Cіtrobacter spp., Campylobacter jejunі, Cardnerella vagіnalіs, Enterobacter spp., Escherіchіa colі, Haemophilus spp.(including strains producing beta lactamase), Hafnіa alveі, Klebsіella spp., Legionella spp., Morganella morganіі, Moraxella catarrhalis (including strains producing beta lactamase); Neisseria gonorrhoeae spp., Proteus spp., Pseudomonas spp., bonejointSalmonella spp., Serratia spp., Shіgella spp., Yersinia enterocolіtіca; Some strains of Stenotrophomonas maltophіlіa can be resistant. Gram-Positive Aerobes: Staphylococcus aureus, Staphylococcus epіdermіdіs, S. Saprophyticus, S. Pyogenes (А group streptococcus); Streptococcus agalactіae (В group streptococcus), S. Pneumoniae, Viridans group streptococci.
Anaerobes: Bacteroides spp. except Bacteroides fragilis , including B. melanіnogenіcus and other oral cavity microorganisms referred to bacteroides; Clostridium perfrіngens; Fusobacterіum spp.; Venus Remedies Limited | Confidential Page 27 of 64
Mobіluncus spp.; Peptostreptococcus spp.; Veіllonella spp; Potentox is not active against Bacteroides fragilis and Clostridium dіffіcіle.

 

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